June 15, 2026
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The fountain of youth might not be real, but the science behind Medik8‘s latest skin care launch is.

The British brand used by stars like Rosie Huntington-Whiteley and Hailey Bieber recently rolled out an advanced serum that promises to target multiple signs of aging — yet is so gentle, it can even be used post-procedure.

The new Exo-PDRN Primastic+ Youthful Vitality Serum visibly improves radiance, tone and overall skin vitality using the buzziest of clinically-backed ingredients, like a proprietary exosome complex and a vegan version of PDRN, which is typically derived from salmon sperm DNA.

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A white bottle of Medik8 EXO-PDRN Prismatic+ Youthful Vitality Serum.
Medik8

Promising clinical-grade results, the Exo-PDRN Primastic+ Serum counters redness while strengthening the skin barrier and improving the look of wrinkles and sagging, all while imparting luminosity. (The before-and-after pics are impressive.)

With all the buzz around these trendy ingredients, we asked Manhattan-based Dr. Jennifer Levine for her professional perspective.

“PDRN acts as a powerful biostimulator that triggers DNA repair and aggressively cuts down inflammation,” according to the anti-aging expert — making it a great choice for post-procedure, and for countering redness.


Rosie Huntington-Whiteley in a white oversized collared top.
Rosie Huntington-Whiteley is a Medik8 fan. Rosie Huntington-Whiteley/Instagram

Likewise, the NYC doc shared that the exosomes deliver a concentrated cocktail “directly to cells to accelerate collagen production. Together, they reset the cellular aging clock — making them a game changer for rapid healing and long-term tissue restoration.” (Well, we’re adding to cart after this!)

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On the Medik8 website, Exo-PDRN Primastic+ Serum has a near-perfect rating with nearly 1,200 reviews already.

“I’ve only been using Exo-PDRN for a week, and my skin already looks different — smoother and more radiant,” reads one.

“After several weeks of use, my skin looked brighter, smoother, and more resilient, with a noticeable improvement in overall radiance,” echoed another customer.

Scroll on to shop a few more best sellers from the brand, including Huntington-Whiteley’s go-to r-Retinoate Day & Night.



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